VERIFIED · USA
TB-500
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What TB-500 is studied for.
Thymosin β4 fragment. Investigated across the following preclinical and in-vitro research areas.
Cardiac repair
Studied in preclinical and in-vitro research for cardiac-tissue repair.
Tissue regeneration
Studied in preclinical and in-vitro research for tissue regeneration and recovery.
Wound healing
Studied in preclinical and in-vitro research for wound healing and anti-inflammatory response.
Hair growth
Studied in preclinical and in-vitro research for hair-growth and follicle research.
The science behind TB-500
TB-500 is a synthetic fragment of Thymosin β4, an actin-sequestering protein (ACTA/ACTB/ACTG family). Research has examined its role in cell migration, angiogenesis and tissue regeneration across cardiac, wound-healing and connective-tissue models.
Read the full research picture
- Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UUPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro.PubMed · PMID 38382158
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.PubMed · PMID 41490200
- Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.PubMed · PMID 41476424
- Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.PubMed · PMID 41966639
Targets, pathways and publications are compiled from curated biomedical databases (ChEMBL and pathway resources) and PubMed. They describe directions of laboratory investigation only — not clinical outcomes, efficacy, dosing, or any intended use in humans or animals.
Exactly what's in the vial.
Full molecular Certificate of Analysis — CAS number, molecular formula, weight & sequence — included with every order.
Proof for this exact lot.
VERIFIED
USA
Reconstitution & storage.
General laboratory handling reference for lyophilized peptides. Always follow your institution's protocols.
Equilibrate
Let the sealed vial reach room temperature before opening to prevent condensation.
Add solvent
Slowly add bacteriostatic water down the vial wall — never directly onto the powder.
Dissolve gently
Swirl, don't shake. Let it go fully clear; avoid foaming or vortexing.
Store cold
Refrigerate the reconstituted solution at 2–8°C; minimize freeze-thaw cycles.
Concentration (mg/mL) = vial mass (mg) ÷ solvent added (mL). Use this to plan your working dilutions for in-vitro research.
10 mg ÷ 5 mL = 2 mg/mL
Risk stays with us, not you.
Verified on every lot
Independently tested to its stated purity on the Certificate of Analysis, with a batch-specific CoA included.
Manufactured in the USA 🇺🇸
Synthesized, lyophilized, tested and shipped in the United States.
Free shipment protection
Covered against loss, damage or theft in transit — reshipped at no cost.
What researchers say.
How is the ≥99% purity verified?
What's the best way to store TB-500?
What do I need to reconstitute it?
How fast does it ship?
Is this for human use?
Ready when your research is.
TB-500, ≥99% pure, with a lot-specific CoA and free shipment protection.