VERIFIED · USA
MOTS-C
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What MOTS-C is studied for.
Mitochondrial-derived peptide. Investigated across the following preclinical and in-vitro research areas.
Mitochondrial
Studied as a mitochondrial-derived peptide in metabolic research.
Metabolic regulation
Investigated in insulin-sensitivity models.
Cellular stress
Examined in cellular-stress-response studies.
Reference standard
Used as a research comparator.
The science behind MOTS-C
MOTS-c is a mitochondrial-derived peptide encoded in the 12S rRNA. Research has examined AMPK/PGC-1α signalling and metabolic regulation (FOXO1/3, GLUT4, INSR, NRF1/NFE2L2) in mitochondrial and insulin-sensitivity models.
Read the full research picture
- MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation.PubMed · PMID 36761202
- MOTS-c Functionally Prevents Metabolic Disorders.PubMed · PMID 36677050
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.PubMed · PMID 25738459
- MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.PubMed · PMID 31378979
Targets, pathways and publications are compiled from curated biomedical databases (ChEMBL and pathway resources) and PubMed. They describe directions of laboratory investigation only — not clinical outcomes, efficacy, dosing, or any intended use in humans or animals.
Exactly what's in the vial.
Full molecular Certificate of Analysis — CAS number, molecular formula, weight & sequence — included with every order.
Proof for this exact lot.
VERIFIED
USA
Reconstitution & storage.
General laboratory handling reference for lyophilized peptides. Always follow your institution's protocols.
Equilibrate
Let the sealed vial reach room temperature before opening to prevent condensation.
Add solvent
Slowly add bacteriostatic water down the vial wall — never directly onto the powder.
Dissolve gently
Swirl, don't shake. Let it go fully clear; avoid foaming or vortexing.
Store cold
Refrigerate the reconstituted solution at 2–8°C; minimize freeze-thaw cycles.
Concentration (mg/mL) = vial mass (mg) ÷ solvent added (mL). Use this to plan your working dilutions for in-vitro research.
10 mg ÷ 5 mL = 2 mg/mL
Risk stays with us, not you.
Verified on every lot
Independently tested to its stated purity on the Certificate of Analysis, with a batch-specific CoA included.
Manufactured in the USA 🇺🇸
Synthesized, lyophilized, tested and shipped in the United States.
Free shipment protection
Covered against loss, damage or theft in transit — reshipped at no cost.
What researchers say.
How is the ≥99% purity verified?
What's the best way to store MOTS-C?
What do I need to reconstitute it?
How fast does it ship?
Is this for human use?
Ready when your research is.
MOTS-C, ≥99% pure, with a lot-specific CoA and free shipment protection.