VERIFIED · USA
Semax
What Semax is studied for.
Nootropic ACTH(4-10) analogue. Investigated across the following preclinical and in-vitro research areas.
Cognition
Studied in preclinical and in-vitro research for cognition and cognitive enhancement.
Neuroprotection
Studied in preclinical and in-vitro research for neuroprotection research.
Stroke recovery
Studied in preclinical and in-vitro research for stroke-recovery models.
Optic-nerve research
Studied in preclinical and in-vitro research for optic-nerve and neural research.
The science behind Semax
Semax is a synthetic ACTH(4–10) fragment. Research has focused on BDNF and CNTF neurotrophic signalling and neuroprotection (ARC, CAT) in cognition, stroke-recovery and optic-nerve models.
Read the full research picture
- Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.PubMed · PMID 40692165
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.PubMed · PMID 41490200
- Semax, synthetic ACTH(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats.PubMed · PMID 33418449
- Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.PubMed · PMID 35080861
Targets, pathways and publications are compiled from curated biomedical databases (ChEMBL and pathway resources) and PubMed. They describe directions of laboratory investigation only — not clinical outcomes, efficacy, dosing, or any intended use in humans or animals.
Exactly what's in the vial.
Full molecular Certificate of Analysis — CAS number, molecular formula, weight & sequence — included with every order.
Proof for this exact lot.
VERIFIED
USA
Reconstitution & storage.
General laboratory handling reference for lyophilized peptides. Always follow your institution's protocols.
Equilibrate
Let the sealed vial reach room temperature before opening to prevent condensation.
Add solvent
Slowly add bacteriostatic water down the vial wall — never directly onto the powder.
Dissolve gently
Swirl, don't shake. Let it go fully clear; avoid foaming or vortexing.
Store cold
Refrigerate the reconstituted solution at 2–8°C; minimize freeze-thaw cycles.
Concentration (mg/mL) = vial mass (mg) ÷ solvent added (mL). Use this to plan your working dilutions for in-vitro research.
10 mg ÷ 5 mL = 2 mg/mL
Risk stays with us, not you.
Verified on every lot
Independently tested to its stated purity on the Certificate of Analysis, with a batch-specific CoA included.
Manufactured in the USA 🇺🇸
Synthesized, lyophilized, tested and shipped in the United States.
Free shipment protection
Covered against loss, damage or theft in transit — reshipped at no cost.
What researchers say.
How is the ≥99% purity verified?
What's the best way to store Semax?
What do I need to reconstitute it?
How fast does it ship?
Is this for human use?
Ready when your research is.
Semax, ≥99% pure, with a lot-specific CoA and free shipment protection.




